A conceptual and practical overview of cDNA microarray technology: implications for basic and clinical sciences.

نویسندگان

  • V de Mello-Coelho
  • K L Hess
چکیده

cDNA microarray is an innovative technology that facilitates the analysis of the expression of thousands of genes simultaneously. The utilization of this methodology, which is rapidly evolving, requires a combination of expertise from the biological, mathematical and statistical sciences. In this review, we attempt to provide an overview of the principles of cDNA microarray technology, the practical concerns of the analytical processing of the data obtained, the correlation of this methodology with other data analysis methods such as immunohistochemistry in tissue microarrays, and the cDNA microarray application in distinct areas of the basic and clinical sciences.

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عنوان ژورنال:
  • Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas

دوره 38 10  شماره 

صفحات  -

تاریخ انتشار 2005